Erythropoiesis Abnormalities Contribute to Early-Onset Anemia in Patients with Septic Shock
Occupational injury proneness in Indian women : A survey in fish processing industries
Heart Problems Today
Obstetric Risk Factors Associated with Placenta Previa Development: Case-Control Study
Factors associated with female pattern hair loss and its prevalence in Taiwanese women: A community-based survey
Genetic polymorphism of the adenosine A 2A receptor is associated with habitual caffeine consumption
Clinical malnutrition in severe traumatic brain injury : Factors associated and outcome at 6 months
The prevalence of malnutrition and its risk factors in children attending outpatient clinics in the city of Manaus, Amazonas, Brazil
Critical Success Factors for Implementing Quality Engineering Tools and Techniques in Malaysian's and Indonesian's Automotive Industries: An Exploratory Study
ROAD DESIGN FACTORS AFFECTING DEATH AND SERIOUS INJURY
It has been established that TNF receptor associated factors (TRAFs) are critical signaling mediators for not only the TNF receptor superfamily, but also the interleukin-1 receptor/Toll-like receptor superfamily and the T-cell receptors. They play important roles in mammalian biology including embryonic development, innate and adaptive immune regulation and maintenance of cellular homeostasis. Agents that manipulate the signaling of these receptors are being used or showing promise towards the treatment and prevention of many human diseases such as rheumatoid arthritis, coronary heart disease, transplantation rejection, insulin resistance, multiple organ failure and cancer.
TNF Receptor Associated Factors is the only literature that is entirely devoted to TRAFs. Almost every aspect of TRAF signaling is covered, including the different TRAF family members, their distinct biological functions, the TRAF structures, their modes of receptor recognition, the signaling mechanisms, and the roles of TRAFs in normal cellular functions and in viral infection. TNF Receptor Associated Factors is intended for a wide audience, including researchers in the field of TRAF signaling and students and postdoctoral fellows learning cell biology and cell signal transduction. This exciting new volume is up to date on the most recent advances in TRAF signal transduction.
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