Mass Spectrometry in Drug Metabolism and Pharmacokinetics

This timely reference discusses mass spectrometry in drug metabolism and pharmacokinetic studies. With contributions by professionals from the pharmaceutical industry, this book begins with a review of current mass spectrometry techniques and applications, followed by discussions of various methods for using MS in drug metabolism studies and pharmacokinetics. Highlighting the critical importance of ADME studies for understanding how a drug is absorbed, distributed, metabolized, and excreted by the body, the book s focuses on the use of LC/MS and MALDI-MS. This is a valuable reference for scientists in the pharmaceutical industry, medicine, academia, and even those working in homeland defense.

Customer Reviews:

A good book for MS technologies in PKDM

By Simon Yan - September 14, 2011

This book gives a good introduction of drug metabolism, pharmacokinetics and bioanalytical in pharmaceutical R&D. It also provides information of fundamental LC/MS technologies and typical application examples, such as LC/MS/MS, LC/Q-TOF/MS, LC/ARC/MS, MALD-IMS, in identification of drug metabolites and quantitative analysis. However, this book does not provide detailed information of systematic bioanalytical methods development and validation.