Trend and Opportunities in the Italian Personal Accident and Health Insurance Industry to 2016: Market Profile
Common Diseases and Health Problems in Sheep and Goats
Atmospheric Freeze-Drying of Calanus finmarchicus and its effects on proteolytic and lipolytic activities
No Significant Effects of Lutein, Lycopene or Beta Carotene Supplementation on Biological Markers of Oxidative Stress and LDL Oxidizability in Healthy Adult Subjects
Effects of temperature on the chemical composition and antioxidant activity of three strawberry cultivars
DRYING KINETICS AND ANTIOXIDANT ACTIVITY OF OREGANO
Effect of Sample Preparation Methods and Extraction Time on Yield and Antioxidant Activity from Kradonbok (Careya sphaerica Roxb.) Leaves
CHANGES IN ANTIOXIDANT ACTIVITY OF BLACK CHOKEBERRY JUICE CONCENTRATE SOLUTIONS DURING STORAGE
Antioxidant Activity of Beta-Carotene Related Carotenoids of Peroxyl Radical Mediated Lipid Peroxidation
Traditional Chinese Health Promotion Practices - Qigong and Tai Chi -- in the Prevention and Treatment of Chronic Disease
A state-of-the-science compilation, Lipoic Acid follows the history of this potent coenzyme and the latest discoveries regarding the chemistry, biological action, and significance in energy production, antioxidant activity, and health. The book is divided into three sections:
· Section I: Discovery and Molecular Structure reviews the early studies leading to the discovery of alpha-lipoic acid and explains the molecular structure, biosynthesis, and the characterization of lipoic acid and its chemical derivatives.
· Section II: Metabolic Aspects describes in detail the human pharmacokinetics of alpha-lipoic acid including the lipoic acid-derived dehydrogenase complexes and their roles in energy metabolism. It also explains antioxidant activity and redox modulation and how lipoic acid induces Phase II detoxification enzymes through activation of Nrf2-dependent gene expression.
· Section III Clinical Aspects discusses enzyme deficiency disorders and the effects of lipoic acid on insulin. It defines lipoic acid influence on signaling pathways and AMP-activated kinase, and considers the therapeutic implications for treatment of metabolic syndromes and the improvement of mitochondrial function by lipoic acid supplementation.
Contributions from leading international researchers make Lipoic Acid the most comprehensive, up-to-date account of the impact of this potentially key molecule in diminishing the damaging effects of aging and disease.
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