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Telomerase, an enzyme that maintains telomeres and endows eukaryotic cells with immortality, was first discovered in tetrahymena in 1985. In 1990s, it was proven that this enzyme also plays a key role in the infinite proliferation of human cancer cells. Now telomere and telomerase are widely accepted as important factors involved in cancer biology, and as promising diagnostic tools and therapeutic targets. Recently, role of telomerase in “cancer stem cells” has become another attractive story. Until now, there are several good books on telomere and telomerase focusing on biology in ciliates, yeasts, and mouse or basic sciences in human, providing basic scientists or students with updated knowledge.
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| AVAILABILITY | |||
| Merchant | Format | Price | |
| Amazon US | Paperback | $99.95 - $159.00 | |
| eBooks.com | Digital (PDF) | ||
| eCampus | Paperback | ||
Chemokine Receptors in Cancer (Cancer Drug Discovery and Development)
$60.45 - $159.00Chemokines are a superfamily of low molecular weight cytokines that were initially described based on their ability to induce the directed migration of leukocytes to sites of inflammation or injury. ...
Handbook of Anticancer Pharmacokinetics and Pharmacodynamics (Cancer Drug Discovery and Development)
$139.30 - $278.19Leading investigators synthesize the entire laboratory and clinical process of developing anticancer drugs to create a single indispensable reference that covers all the steps from the identification ...
Macromolecular Anticancer Therapeutics (Cancer Drug Discovery and Development)
$125.82 - $199.00In spite of the development of various anticancer drugs, the therapy of cancer has remained challenging for decades. The current therapy of cancer is overwhelmed because of the inability to ...
Principles of Anticancer Drug Development (Cancer Drug Discovery and Development)
$125.84 - $189.00A practical guide to the design, conduction, analysis and reporting of clinical trials with anticancer drugs.
Methods in Microarray Normalization (Drug Discovery Series)
$73.50 - $99.95Scientists can use molecular profiling microarrays to compare healthy cells with their diseased counterparts and develop gene-specific treatments. Finding the best way to interpret original profiling ...
Oncogene-Directed Therapies, Cancer Drug Discovery & Development Ser
$74.70 - $165.75Oncogene-Directed Therapies, Cancer Drug Discovery & Development Ser
Telomeres and Telomerase - Symposium No. 211
$10.00 - $170.00Telomeres and Telomerase Chairman: Sydney Brenner 1997 Telomeres are the protective genetic elements located at the ends of chromosomes and are essential for correct chromosomal structure and ...
Antiparasitic and Antibacterial Drug Discovery: From Molecular Targets to Drug Candidates (Drug Discovery…
$157.98 - $220.00“… an interesting book that leads the reader through what factors can influence drug discovery and then gives specific examples on the current situation in development of drugs for ...
Cytotoxic Anticancer Drugs: Models and Concepts for Drug Discovery and Development (Developments in…
$47.49 - $353.00The focus of the 22nd Annual Detroit Cancer Symposium was the presentation and discussion of cytotoxic agents, with a significant portion of the symposium including the exciting frontiers of drug ...
The Rho GTPases in Cancer
$83.82 - $179.00The Rho GTPases were first discovered due to their homology to Ras GTPase. Approximately 30% of human cancers harbor an activating mutation to Ras, and Ras mutations promote cell growth and ...
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Genomics and Pharmacogenomics in Anticancer Drug Development and Clinical Response (Cancer Drug Discovery…
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