Case Studies in M2M by David Wigglesworth of Iridium
MEMORANDUM OF AGREEMENT BETWEEN THE OFFICE OF NEW DRUGS AND THE OFFICE OF SURVEILLANCE AND EPIDEMIOLOGY IN THE CENTER FOR DRUG EVALUATION AND RESEARCH
Pharmacokinetics and pharmacodynamics of lipidic nano-particles in ...
Domain and Range of a Function
Analysts' Forecast Accuracy in Germany: The Effect of Different Accounting Principles and Changes of Accounting Principles
Creation and configuration of a Equipment, Facilities, and Preventive Maintenance System utilizing the principles of Lean Documents and Lean Configuration
The Advantages and Disadvantages of Solar Energy - Is Solar Energy the Way Forward?
Biosimilars in Emerging Economies - Advanced Recombinant Technology Platforms and Low Cost Manufacturing Put India and China at a Strategic Advantage in Biosimilar Production
Promises and Perils of Lycopene / Tomato Supplementation and Cancer Prevention
Consideration of Environmental Factors in Transportation Planning: Review and Analysis of Current Policies, Practices and Trends
Following an introduction to the role of PK and PD in the development of biotech drugs, the book goes on to cover the basics, including the pharmacokinetics of peptides, monoclonal antibodies, antisense oligonucleotides, as well as viral and non-viral gene delivery vectors. The second section discusses such challenges and opportunities as pulmonary delivery of proteins and peptides, and the delivery of oligonucleotides. The final section considers the integration of PK and PD concepts into the biotech drug development plan, taking as case studies the preclinical and clinical drug development of tasidotin, as well as the examples of cetuximab and pegfilgrastim.
The result is vital reading for all pharmaceutical researchers.
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