The Impact of a Renal Dosing Service on Dosage Adjustment in CKD: Impleminting a service and evaluating its outcomes

Patients with chronic kidney disease (CKD) often have alterations in their pharmacokinetic and pharmacodynamic response. They constitute a population at high-risk for adverse drug reactions and drug-drug interactions. Drug dosing in these patients is a very challenging task. This book, therefore, implements a dosing service by a clinical pharmacist and evaluates its outcomes. It includes an introduction to CKD and the steps for suitable drugs' use and dosing, and then it includes methods, outcomes, discussion and conclusions related to the service. Part of the study was to utilize a collection of reliable and up-to-date references that are commonly used globally to develop a pocket size handbook for dosing recommendations related to renal impairment - if present- and removal by dialysis. These tables are available by the end of this book and they can be very useful to guide suitable dosing. This book can be useful for nephrologists, other physicians and pharmacists to help in providing the suitable dosages of medications according to patients' renal functions. It can be useful also for researchers and postgraduate students in this field.