An Error Was Encountered

Error Number: 1054

Unknown column 'cache_on' in 'field list'

UPDATE `aff_pdf_cache` SET `cache` = 'a:10:{i:0;O:8:\"stdClass\":13:{s:2:\"id\";s:6:\"495065\";s:6:\"status\";s:8:\"verified\";s:11:\"author_name\";s:5:\"shaun\";s:9:\"author_id\";s:1:\"0\";s:14:\"author_website\";s:73:\"http://www.transparencymarketresearch.com/human-embryonic-stem-cells.html\";s:5:\"title\";s:76:\"Human Embryonic Stem Cells Market - Growth, Trends and Forecast, 2013 - 2019\";s:11:\"description\";s:378:\"Human embryonic stem cells (hESCs) are derived from blastocyst and are capable of differentiating into number of cell types that make up the human body. hESCs can replicate indefinitely and produce non-regenerative tissues such as neural and myocardial cells. These abilities of human embryonic stems cells allow them to be used as a tool in regenerative medicine and research.\n\";s:5:\"thumb\";s:88:\"images/t/4951/human-embryonic-stem-cells-market-growth-trends-and-forecast-2013-2019.jpg\";s:6:\"thumb2\";s:89:\"images/t2/4951/human-embryonic-stem-cells-market-growth-trends-and-forecast-2013-2019.jpg\";s:9:\"permalink\";s:70:\"human-embryonic-stem-cells-market-growth-trends-and-forecast-2013-2019\";s:5:\"pages\";s:1:\"4\";s:6:\"rating\";s:1:\"0\";s:5:\"voter\";s:1:\"0\";}i:1;O:8:\"stdClass\":13:{s:2:\"id\";s:4:\"2348\";s:6:\"status\";s:8:\"verified\";s:11:\"author_name\";s:6:\"shinta\";s:9:\"author_id\";s:3:\"377\";s:14:\"author_website\";s:0:\"\";s:5:\"title\";s:32:\"Adult Stem Cells Aid Broken Bone\";s:11:\"description\";s:605:\"Adult stem cells are specialized cells with the ability to regenerate tissue in response to damage. However, many patients lack sufficient numbers of these cells and thus cannot heal properly.
\nResearchers have used adult stem cells in a few cases to improve fracture healing, but further studies were needed to show that this method was truly effective and safe before it can be pursued as a new treatment. Now scientists at UNC have provided the scientific foundation for future clinical trials of this approach by demonstrating in animal models that these cells can be used to repair broken bones.\";s:5:\"thumb\";s:48:\"images/t/24/adult-stem-cells-aid-broken-bone.jpg\";s:6:\"thumb2\";s:49:\"images/t2/24/adult-stem-cells-aid-broken-bone.jpg\";s:9:\"permalink\";s:32:\"adult-stem-cells-aid-broken-bone\";s:5:\"pages\";s:1:\"3\";s:6:\"rating\";s:3:\"2.5\";s:5:\"voter\";s:1:\"2\";}i:2;O:8:\"stdClass\":13:{s:2:\"id\";s:4:\"2703\";s:6:\"status\";s:8:\"verified\";s:11:\"author_name\";s:6:\"shinta\";s:9:\"author_id\";s:3:\"377\";s:14:\"author_website\";s:0:\"\";s:5:\"title\";s:122:\"Efficacy of the Mobilization of Peripheral Blood Stem Cells by Granulocyte Colony - Stimulating Factor in Pediatric Donors\";s:11:\"description\";s:1341:\"The advantages/disadvantages of the use of peripheral blood stem cells
\n(PBSCs) for allogeneic transplantation still need to be clarified, particularly
\nin children. We compared the kinetics, efficacy, and safety of PBSC
\nmobilization by granulocyte colony-stimulating factor (G-CSF) and collection
\nby apheresis between healthy pediatric and adult donors. A total of
\n19 pediatric (median age, 6 years) and 25 adult healthy donors (median
\nage, 37 years) were given 10 mg/kg/day of G-CSF for 5 consecutive days
\nfor PBSC mobilization, which were harvested by apheresis on days 5
\nand/or 6. All of the donors tolerated the whole procedures. Serum trough
\nlevels of G-CSF determined by ELISA were significantly lower in the 16
\npediatric donors evaluated than in adults (n 5 16) on days 3 and 4
\n(P < 0.05). Although the WBC counts on days 4 and 5 were significantly
\nhigher in adults than in children (P 5 0.006 and 0.004, respectively), the
\nnumbers of circulating CD341 cells/unit of blood were identical. The
\nnumber of blood CD341 cells collected per unit of blood processed was
\nidentical in both donor populations. We propose that PBSCs could be
\neffectively mobilized and collected in small children so that they could be
\ndonors for adult patients.\";s:5:\"thumb\";s:136:\"images/t/28/efficacy-of-the-mobilization-of-peripheral-blood-stem-cells-by-granulocyte-colony-stimulating-factor-in-pediatric-donors.jpg\";s:6:\"thumb2\";s:137:\"images/t2/28/efficacy-of-the-mobilization-of-peripheral-blood-stem-cells-by-granulocyte-colony-stimulating-factor-in-pediatric-donors.jpg\";s:9:\"permalink\";s:120:\"efficacy-of-the-mobilization-of-peripheral-blood-stem-cells-by-granulocyte-colony-stimulating-factor-in-pediatric-donors\";s:5:\"pages\";s:1:\"4\";s:6:\"rating\";s:1:\"0\";s:5:\"voter\";s:1:\"0\";}i:3;O:8:\"stdClass\":13:{s:2:\"id\";s:5:\"75721\";s:6:\"status\";s:8:\"verified\";s:11:\"author_name\";s:9:\"henriette\";s:9:\"author_id\";s:1:\"0\";s:14:\"author_website\";s:0:\"\";s:5:\"title\";s:69:\"Pancreatic Cancer Stem cells: New Direction for Pancreatic Cancer ...\";s:11:\"description\";s:423:\"Emerging evidence suggests malignant tumors are composed of a small subset of distinct cancer cells, termed cancer stem cells. Cancer stem cells have the ability to self-renew and to also initiate and propagate tumors. Data have been provided to support the existence of cancer stem cells in human blood cell-derived cancers and solid tissue tumors of the breast, prostate, brain, pancreas, head and neck, skin, and colon. \";s:5:\"thumb\";s:81:\"images/t/758/pancreatic-cancer-stem-cells-new-direction-for-pancreatic-cancer.jpg\";s:6:\"thumb2\";s:82:\"images/t2/758/pancreatic-cancer-stem-cells-new-direction-for-pancreatic-cancer.jpg\";s:9:\"permalink\";s:64:\"pancreatic-cancer-stem-cells-new-direction-for-pancreatic-cancer\";s:5:\"pages\";s:1:\"7\";s:6:\"rating\";s:1:\"0\";s:5:\"voter\";s:1:\"0\";}i:4;O:8:\"stdClass\":13:{s:2:\"id\";s:6:\"469203\";s:6:\"status\";s:8:\"verified\";s:11:\"author_name\";s:5:\"Marca\";s:9:\"author_id\";s:1:\"0\";s:14:\"author_website\";s:0:\"\";s:5:\"title\";s:50:\"Easier Method Discovered for Generating Stem Cells\";s:11:\"description\";s:125:\"The Centre of Regenerative Medicine in Barcelona has managed to simplify the method for creating stem cells from adult cells.\";s:5:\"thumb\";s:68:\"images/t/4693/easier-method-discovered-for-generating-stem-cells.jpg\";s:6:\"thumb2\";s:69:\"images/t2/4693/easier-method-discovered-for-generating-stem-cells.jpg\";s:9:\"permalink\";s:50:\"easier-method-discovered-for-generating-stem-cells\";s:5:\"pages\";s:1:\"1\";s:6:\"rating\";s:1:\"0\";s:5:\"voter\";s:1:\"0\";}i:5;O:8:\"stdClass\":13:{s:2:\"id\";s:5:\"75724\";s:6:\"status\";s:8:\"verified\";s:11:\"author_name\";s:4:\"joel\";s:9:\"author_id\";s:1:\"0\";s:14:\"author_website\";s:0:\"\";s:5:\"title\";s:51:\"Notch Promotes Radioresistance of Glioma Stem Cells\";s:11:\"description\";s:686:\"Radiotherapy represents the most effective nonsurgical treatments for gliomas. However, gliomas are highly radio resistant and recurrence is nearly universal. Results from our laboratory and other groups suggest that cancer stem cells contribute to radio resistance in gliomas and breast cancers. The Notch pathway is critically implicated in stem cell fate determination and cancer. In this study, we show that inhibition of Notch pathway withc-secretase inhibitors (GSIs) renders the glioma stem cells more sensitive to radiation at clinically relevant doses. GSI senhance radiation-induced cell death and impair clonogenic survival of glioma stem cells but not non-stem glioma cells.\";s:5:\"thumb\";s:68:\"images/t/758/notch-promotes-radioresistance-of-glioma-stem-cells.jpg\";s:6:\"thumb2\";s:69:\"images/t2/758/notch-promotes-radioresistance-of-glioma-stem-cells.jpg\";s:9:\"permalink\";s:51:\"notch-promotes-radioresistance-of-glioma-stem-cells\";s:5:\"pages\";s:2:\"12\";s:6:\"rating\";s:1:\"0\";s:5:\"voter\";s:1:\"0\";}i:6;O:8:\"stdClass\":13:{s:2:\"id\";s:5:\"75747\";s:6:\"status\";s:8:\"verified\";s:11:\"author_name\";s:7:\"bellino\";s:9:\"author_id\";s:1:\"0\";s:14:\"author_website\";s:0:\"\";s:5:\"title\";s:38:\"Cancer Stem Cells in Pancreatic Cancer\";s:11:\"description\";s:525:\"Pancreatic cancer is an aggressive malignant solid tumor well-known by early metastasis, local invasion, resistance to standard chemo- and radiotherapy and poor prognosis. Increasing evidence indicates that pancreatic cancer is initiated and propagated by cancer stem cells (CSCs). Here we review the current research results regarding CSCs in pancreatic cancer and discuss the different markers identifying pancreatic CSCs. This review will focus on metastasis, microRNA regulation and anti-CSC therapy in pancreatic cancer.\";s:5:\"thumb\";s:55:\"images/t/758/cancer-stem-cells-in-pancreatic-cancer.jpg\";s:6:\"thumb2\";s:56:\"images/t2/758/cancer-stem-cells-in-pancreatic-cancer.jpg\";s:9:\"permalink\";s:38:\"cancer-stem-cells-in-pancreatic-cancer\";s:5:\"pages\";s:2:\"13\";s:6:\"rating\";s:1:\"0\";s:5:\"voter\";s:1:\"0\";}i:7;O:8:\"stdClass\":13:{s:2:\"id\";s:6:\"167881\";s:6:\"status\";s:8:\"verified\";s:11:\"author_name\";s:5:\"ccstb\";s:9:\"author_id\";s:5:\"45780\";s:14:\"author_website\";s:0:\"\";s:5:\"title\";s:37:\"Umbilical Cord Banks Blood Stem cells\";s:11:\"description\";s:277:\"Discusses the use of umbilical cord blood stem cells to treat diseases as an alternative to bone marrow transplants \n\nand why donating stem cells from the placenta and umbilical cord to cord blood banks is an important and safe \n\ndecision that does not harm the mother or baby.\";s:5:\"thumb\";s:55:\"images/t/1679/umbilical-cord-banks-blood-stem-cells.jpg\";s:6:\"thumb2\";s:56:\"images/t2/1679/umbilical-cord-banks-blood-stem-cells.jpg\";s:9:\"permalink\";s:37:\"umbilical-cord-banks-blood-stem-cells\";s:5:\"pages\";s:1:\"8\";s:6:\"rating\";s:1:\"0\";s:5:\"voter\";s:1:\"0\";}i:8;O:8:\"stdClass\":13:{s:2:\"id\";s:6:\"373779\";s:6:\"status\";s:8:\"verified\";s:11:\"author_name\";s:11:\"researchmoz\";s:9:\"author_id\";s:6:\"550912\";s:14:\"author_website\";s:26:\"http://www.researchmoz.us/\";s:5:\"title\";s:78:\"Circulating Tumor Cells (CTCs) and Cancer Stem Cells (CSCs) 2013 Market Report\";s:11:\"description\";s:111:\"Researchmoz.us add Circulating Tumor Cells (CTCs) and Cancer Stem Cells (CSCs) 2013 Market Report to its store.\";s:5:\"thumb\";s:92:\"images/t/3738/circulating-tumor-cells-ctcs-and-cancer-stem-cells-cscs-2013-market-report.jpg\";s:6:\"thumb2\";s:93:\"images/t2/3738/circulating-tumor-cells-ctcs-and-cancer-stem-cells-cscs-2013-market-report.jpg\";s:9:\"permalink\";s:74:\"circulating-tumor-cells-ctcs-and-cancer-stem-cells-cscs-2013-market-report\";s:5:\"pages\";s:1:\"9\";s:6:\"rating\";s:1:\"0\";s:5:\"voter\";s:1:\"0\";}i:9;O:8:\"stdClass\":13:{s:2:\"id\";s:6:\"393587\";s:6:\"status\";s:8:\"verified\";s:11:\"author_name\";s:9:\"benturner\";s:9:\"author_id\";s:5:\"82024\";s:14:\"author_website\";s:0:\"\";s:5:\"title\";s:68:\"Regenerative medicine and Stem cells Partnering Terms and Agreements\";s:11:\"description\";s:160:\"This report provides details of the latest regenerative medicine and stem cells agreements including cell therapy agreements announced in the healthcare sector.\";s:5:\"thumb\";s:86:\"images/t/3936/regenerative-medicine-and-stem-cells-partnering-terms-and-agreements.jpg\";s:6:\"thumb2\";s:87:\"images/t2/3936/regenerative-medicine-and-stem-cells-partnering-terms-and-agreements.jpg\";s:9:\"permalink\";s:68:\"regenerative-medicine-and-stem-cells-partnering-terms-and-agreements\";s:5:\"pages\";s:1:\"4\";s:6:\"rating\";s:1:\"0\";s:5:\"voter\";s:1:\"0\";}}', `cache_on` = '2015-02-28 01:54:29' WHERE `aff_id` = '20192'