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Assessment of Electroceutical Treatment for Ovarian Cysts And Concomitant Symptoms

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The mechanisms of action and clinical applications of specific-parameter electrical fields (electroceutical medicine) in the treatment of ovarian cysts and concomitant symptoms are reviewed. Possible mechanisms of action include an increased level of cyclic AMP, stimulation of endorphin release, anti-inflammatory action, and steroidogenesis resulting from normalization of intercellular communication. Favorable results in the clinical setting were achieved in the treatment of ovarian cysts. Treatment success was reflected in a significant reduction in overall cyst sizes as well as amelioration of various concomitant symptoms, including fever, chills, inflammation, and abdominal pain. Specific electroceutical treatment was shown to have potent analgesic and anti-inflammatory effects. No adverse effects have been reported.
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Content Preview
Advances
Vol. 8, No. 5
In Therapy® September/October 1991


Assessment of Electroceutical
Treatment for Ovarian Cysts
And Concomitant Symptoms

Francois Savery, M.D.
Family Practice
USA

Richard Sorgnard, Ph.D.
Pain Management
USA

Frank Silver, M.D.
Randall Edward, M.D.
Obstetrics/Gynecology
USA

Albert Fann, M.D.
Obstetrics/Gynecology
New Zealand

Robert Mann, M.D.
Obstetrics/Gynecology
Australia

Chris Rogers, M.D.
Radiology
USA

H.U. May, M.D.
Neurology
Germany

LAKE MEAD HOSPITAL MEDICAL CENTER
North Las Vegas Nevada

ABSTRACT:

The mechanisms of action and clinical applications of specific-parameter electrical fields
(electroceutical medicine) in the treatment of ovarian cysts and concomitant symptoms are
reviewed. Possible mechanisms of action include an increased level of cyclic AMP, stimulation of
endorphin release, anti-inflammatory action, and steroidogenesis resulting from normalization of
intercellular communication. Favorable results in the clinical setting were achieved in the
treatment of ovarian cysts. Treatment success was reflected in a significant reduction in overall
cyst sizes as well as amelioration of various concomitant symptoms, including fever, chills,
inflammation, and abdominal pain. Specific electroceutical treatment was shown to have potent
analgesic and anti-inflammatory effects. No adverse effects have been reported.
Keywords: Electroceutical medicine; cyclic AMP; endorphins; anti-inflammatory action;
steroidogenesis; ovarian cysts


Introduction:


Electroceutical medicine is a well-documented medical treatment with both stimulating and
healing effects. Electroceutical medicine facilitates individualization of electromedical treatment
according to the pathogenesis and pathophysiology of the symptoms present. The desired
treatment effect, i.e., anti-inflammatory action, is then converted to the appropriate mode and
delivered safely and non-traumatically into the patient's body. Correct anatomical localization of
the desired treatment effect is ensured by following established treatment protocols and suggested
medical/scientific guidelines.

Two main classes of physiological effects have been categorized and described by the Clinical
Electromedical Research Academy (CERA). First, Stimulatory Class (St) effects -- the
physiological effects achieved by inducing repeated action impulses (depolarization and
repolarization activity) in excitable cells, and second, Multi-facilitory Class (Mf) effects -- all
other physiological effects occurring in the body without inducing repeated action impulses. All
effects are accomplished with regard to both systemic and local patient-tolerance thresholds.

Specific electroceuticals are capable of producing healing effects in deep-tissue structures.
This is accomplished by summating an optimum intensity-dosage and delivering it
unidirectionally into the depths of the tissue for correct anatomical placement and desired
treatment effects. Electroceuticals are associated with regeneration, enhanced facilitation of
metabolism, diffusion and filtration processes, and potent analgesia (including neuron blockade).


Electroceutical Medicine and Ovarian Cysts:


Eighteen female patients with ovarian cysts confirmed by diagnostic ultrasound were selected
for electroceutical treatment. Patients ranged in age from 18 to 36 years and had a minimum 2-
year history of ovarian cysts measuring 4.2 to 5 cm without any interim decrease in overall cyst
size. Patients were symptomatic, with moderate to severe lower abdominal pain, fever, and
noticeable inflammation. All patients refused continued treatment with antibiotics, hormones, or
surgical intervention. The established treatment was administered daily for 15 - 20 minutes
(Monday through Friday) at an intensity level that exceeded the sensory perception threshold but
remained below motor threshold. In all cases, fever, chills, and pain subsided after 3 days of
treatment. By the 8th treatment total remission was obtained subjectively. After the 15th
treatment (designated as the full therapeutic course for this study), repeat diagnostic pelvic
ultrasound revealed the absence of ovarian cysts or a reduction in size to 0.5 cm. Figures 1
through 4 illustrate the response of two patients to treatment. It is hypothesized that treatment
success in our patients was mediated by anti-inflammatory action, increased levels of cyclic AMP,
stimulated release of endorphins, and improved intercellular communication enhancing
steroidogenesis in the gonads.


Discussion:


Electroceutical treatment of ovarian cysts and concomitant symptoms is based on the effect of
cyclic AMP as well as on steroidogenesis in the gonads. Suppression of ovarian cyst symptoms,
reduction in ovarian cyst size, suppression of painful menstrual cramps, and facilitation of free
menstrual flow are related to stimulation of progesterone synthesis in the corpus luteum by
luteinizing hormone (LH) in a way that closely parallels the adrenal system. Marsh and Savard
(1964) established an in vitro system with bovine corpus luteum slides that responded to LH, and
then performed a series of experiments designed to determine if the Haynes hypothesis was
applicable to the corpus luteum. Haynes found that LH specifically increased the activity of luteal
phosphorylase concomitant with an increased steroidogenesis and that exogenous cyclic AMP
stimulated progesterone synthesis. In addition, they found that cyclic AMP caused the same
pattern of incorporation of radioactive steroid precursor as LH.

In collaborating experiments, Marsh et al, 1966, studied the relationship between cyclic AMP
and steroidogenesis in the corpus luteum. Those results appear to indicate that LH increased
cyclic AMP levels before progesterone synthesis. LH was inactivated. by exposure to hydrogen
peroxide at room temperature; prolactin, ACTH, epinephrine, and glucagon failed to stimulate
either cyclic AMP accumulation or steroidogenesis. Therefore, it appears that electroceutical
medical treatment works in a similar way to suppress symptoms of ovarian cysts.

This study dealt with clinically common cysts measuring more than 4 cm. Cysts may be
single but are usually multiple, and can be either benign or malignant. Typically, cysts larger than
4 cm are associated with painful abdomen, fever, chills, and amenorrhea or menorrhalgia.


Ovarian cysts can be simple, follicular, or luteal. Follicular cysts are so commonplace that
they are often considered physiologic variants.

None of the 18 patients participating in this study received any oral or intra-muscular
pharmacological treatment. The subjective patient response was almost immediate relief of pain
and reduced “bloated” feeling. All experienced relief from menstrual cramps followed by free
menstrual flow. A possible explanation involves the actions of hypophysiotropic hormone
together with certain other neuropeptides such as Substance P neurotensin, and endorphins that
constitute a class of neurotransmitters.

It is also hypothesized that electroceutical treatment has the following direct and
indirect effects on cysts:
1. Normalization of pathologic metabolic processes in the abnormal cystic lesion,
probably mediated by electric conformation changes within the cell membrane
(imitation of hormone effects), causing second messenger formation (cyclic AMP).

2. Direct influences on cell communication, for instance, a “cleaning effect” on gap
junction channels, resulting in partial or total restoration of intercellular
communication processes that assists in enhancing steroidogenesis.

3. Facilitation of all metabolic processes in general, such as equilibration of metabolic
concentration differences and increased kinetic energy of molecules.
4. Activation or normalization of immune system cells that could increase phagocytic
activity and the release of substances inhibiting cyst growth.
5.
Stimulation of the sympathetic nervous system leads to norepinephrine release.
Norepinephrine activates adenylate cyclase, which causes an elevation in cyclic
AMP in all cells involved in anticystic activity.



CONCLUSION


We have presented and discussed the application of electroceutical medical treatment for
ovarian cysts and concomitant symptoms. Favorable results were achieved in all patients
receiving treatment, with no report of adverse side effects. It is also probable that the cysts might
have undergone enlargement in size and/or malignancy in the absence of treatment.

It has been demonstrated that electroceutical treatment results in synthesis of progestational
steroids in response to LH. Other well-documented studies (Dorrington et al) have provided
considerable evidence for the involvement of cyclic AMP in the treatment of ovarian disease.
Exogenous cyclic AMP specifically stimulates steroidogenesis. Explicit electromedical treatment
has been shown to increase the level of cyclic AMP by as much as 500% (Brighton et al). We
believe that our success in reducing ovarian cyst size and resolving concomitant symptoms
primarily resulted from increased levels of cyclic AMP,

The advantages of electroceutical medical treatment in the management of ovarian cysts and
concomitant symptoms are presented herein for the first time in the medical literature. Although
no adverse effects were found in any patient, we suggest caution in the application of these
treatment modalities to more selected cases and in other areas. We believe that there is enough
evidence to support the use of electroceutical medicine in all areas of ovarian cysts and related
pathology. It would be wise to note that even in cases of ovarian cyst where surgical intervention
is deemed necessary, the overall reduction in cyst size would undoubtedly benefit the surgeon in
completing the procedure. Finally, we believe that electroceutical medical treatment places us on
the threshold of discovery: it is time to apply our knowledge in all clinical settings.









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