Discover African Jobelyn
Antioxidant Powerhouse!
• Joint Health
• Immune System
Support
• Cardiovascular
Health
• Red Blood Cell
Development
Discover Jobelyn – A traditional
African preparation of Sorghum bicolor.
Both in its African homeland and in North America, a folk remedy
herbal extract has recently caught the attention of medical
researchers. Sorghum bicolor is a grain long known for its high
nutritional value. But only a special traditional extract of the leaf sheath
draws out the plant’s incredible health benefits.
African tribal culture has long touted the extract for its value in helping
people who struggle with anemia, heart disease, joint pain, and poor
immune system response. Today’s scientific studies are quickly confirming
Blueberries, pomegranate, grapeseed, açai
those folk uses. Yet, one must ask, “How can a single herbal ingredient
berry… and many more. Everywhere
help with such a broad range of conditions?”
you turn, familiar and not-so-familiar
The secret is the extract’s sky-high antioxidant rating and anti-
foods and herbs are touted for their
inflammatory effects. One company has made Sorghum bicolor leaf extract
“antioxidant strength.” With all the buzz
available to the U.S. market under the name Jobelyn™. The product has
about antioxidants these days, it can be
an Oxygen Radical Absorbance Capacity (ORAC) of 3,123 µmoleTE/g.
overwhelming to choose the one that is
That’s three times that of açai berries! Complementing that antioxidant
right for you.
rating is Jobelyn’s anti-inflammatory effect. The extract has demonstrated
Besides, what are antioxidants? How can
selective COX-2 inhibition, providing effective reduction in inflammation
they be so helpful for so many health
without the side effects of common prescription medications.
conditions? Are they just a trendy health fad?
In short, all the conditions that Jobelyn addresses look unrelated, but they
Let’s answer those questions while looking
actually have two major factors in common. They are all tied closely to
at one antioxidant source in particular that
underlying states of cyclical inflammation and oxidative damage. Let’s
could provide you and your family with
take a closer look at oxidative and inflammatory processes in the body.
incredible health-changing benefits.
Then it will be easier to understand how the extract supports such a
wide variety of systems and functions.
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Antioxidants:
Inflammation:
Working to protect the body on a cellular level
When the body’s crisis switch gets stuck in the “on” position
Oxidation. We know it’s a bad
Jobelyn, a traditional Sorghum bicolor leaf
The other core benefit of Jobelyn is its anti-
thing for the body, and doctors
extract demonstrates an ORAC rating two times
inflammatory effect. It’s important to have a
tell us to eat lots of antioxidant
the total value of 13 antioxidant foods!
basic understanding of the inflammation process.
fruits and vegetables. But how
(ORAC) per mg.
Typically, when inflammation first occurs, it’s a
does oxidation happen anyway?
Blueberries
24.00 mmoleTE/g
good thing. Inflammation is the body’s standard
We need oxygen for life. Our
Plums
9.49 mmoleTE/g
response to injury or infection. When there’s
Blackberries
20.36
lungs take it in, and a complex
mmoleTE/g
a crisis in the body—whether that’s a sprained
Oranges
7.50 mmoleTE/g
network of capillaries and
Frozen Tart Cherries
20.33
ankle, a torn ligament, or a case of the flu—the
mmoleTE/g
alveoli enable red blood cells
Red Grapes
7.39 mmoleTE/g
body gears up, sending extra white blood cells and other immune system
to acquire the oxygen and
Açai Berries
997.00 mmoleTE/g
components to the place or places where there is a problem. That’s
deliver it throughout the
Strawberries
15.00 mmoleTE/g
why an injury site swells up or your glands get big when you’re sick.
body. But, as oxygen is used
Dried Tart Cherries
68.00 mmoleTE/g
Inflammation hurts, and the pain is the body’s way of demanding that
in various processes, tiny
Tart Cherry Juice
128.00 mmoleTE/g
Concentrate
you rest the injured part or get extra sleep.
electrons can break off. These
Canned Water-packed
17.00 mmoleTE/g
unpaired electrons are called
Tart Cherries
Inflammation is an intelligent system that, when working properly,
free radicals. Think of them as
Prunes
57.70 mmoleTE/g
initiates the first healing stages in response to an injury or illness.
the waste product of cellular
Raspberries
12.20 mmoleTE/g
However, sometimes the inflammation cycle won’t calm down. One
processes.
JOBELYN
3,123.00 mmoleTE/g
of the most common examples is that of a joint injury that continues to
Jobelyn has more proven Oxidative Radical Absorbance Capacity
cause pain long after the original injury has healed. An ongoing state of
There are some processes
(ORAC) than 13 well-known antioxidant-rich fruits–combined!
inflammation can take the shape of degenerative diseases like arthritis. A
where free radicals are actually a good thing – for instance, to kill
hair trigger inflammation response is also at the core of allergic reactions
bad bacteria in certain immune system functions. But, generally free
and many asthma cases. So, not all inflammation is bad. But when
radicals are not helpful. They bounce around hitting cells and causing
damage, sometimes even breaking off portions of DNA. The grand
inflammation won’t stop, or it happens in an unproductive manner (ie.
sum of this cellular damage is at the root of many health conditions
allergies, asthma, rheumatoid arthritis), it can drastically limit people and
including cardiovascular challenges, poor immune response, and even the
threaten their quality of life.
appearance of wrinkles on the skin. This is the cumulative wear and tear
Scientists have found a group of enzymes involved in inflammation and
that results from simply living life. Oxidation is also aggravated by stress,
other processes in the body. These enzymes are referred to as the COX
environmental factors, and poor diet.
(Cyclooxygenase) enzymes. One in particular, COX-2, is a major player
The effects can be tempered though, through a diet and supplement
in the bio-chemical cascade that results in inflammation and resulting
program rich in antioxidants. Just like it sounds, an antioxidant is a
pain.
substance that naturally combats oxidation. Antioxidants are substances
Common non-steroidal anti-inflammatory drugs (NSAIDs) inhibit all
that bind up the stray electrons and render them harmless. Antioxidant
COX enzymes. This is called non-selective COX-inhibition. Ongoing
foods and dietary supplements are rated using the ORAC scale, which
use typically results in unwanted side effects such as peptic ulcers—an
is a measure of the substance’s ability to absorb free radicals. When
inflammatory condition in itself. That’s a sad situation; having decreased
compared to other recommended antioxidant foods, Jobelyn boasts
inflammatory pain in one part of the body, you wind up inadvertently
one of the highest food-source ORAC ratings known. That makes it a
causing inflammation elsewhere!
superior choice for antioxidant supplementation.
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This is where Jobelyn comes in. Thankfully, some natural herbal sources
benefit too. Some researchers believe that sickle red cells can provoke
have been found to exhibit selective inhibition for COX-2 only—the
inflammation throughout the circulatory system because the deformed
COX enzyme that is most active in the inflammation process. The
cells physically hinder smooth blood flow.9 Jobelyn works both at the
traditional African extract of Sorghum bicolor is one of these herbal
level of protecting the red blood cells from oxidation and on the level of
sources. Acting as a proven selective COX-2 inhibitor, Jobelyn soothes
protecting the circulatory system from the inflammation state that can
the inflammation cycle and brings it to a centered state.1, 2 Rather than
create even more free radicals. This herbal remedy cuts off the cycle of
acting as a pain-killer only, masking the symptoms, it works at the level of
oxidation and inflammation that aggravates sickle cells. While it can’t
the inflammation process itself hindering COX-2 activity. This selective
cure the physical shape and structure of the sickle cells, it can lessen the
COX-2 inhibition results in a steady reduction of inflammation and pain,
damage and effects of the cell deformity.
without the unwanted side effects common with NSAIDs.
Cardiovascular Health – Seeing how helpful
Applying the Science:
Jobelyn is for the stressed circulatory system in
Sickle Cell Disease patients, it’s a small step to
How Sorghum bicolor leaf extract helps specific conditions
recognize how helpful it is for cardiovascular
Blood Cell Health – Jobelyn provides
health in general. The medical community
strong antioxidant support for red blood cells.
now views free radical oxidation and ongoing
Understanding the oxidation process, it’s easy to
inflammation as primary contributors to heart
see how red blood cells might be particularly
disease, cholesterol build-up, and arteriosclerosis (severe thickening and
vulnerable to the damaging effects of oxygen
hardening of artery walls).
radicals. Red blood cells are the body’s oxygen
Just as red blood cells are exposed to lots of free radicals, so are heart
carriers. In the course of their 120-day lifespan,
and blood vessel cells. Heart cells also have the added stress of being
they are constantly in contact with this double-
involved in constant contraction. This muscle activity produces plenty
edged sword – the element that we require for life, which is also the
of free radicals as a byproduct. Antioxidant protection is vital for the
origin of oxidation. Adding to the challenge is the fact that mature red
cardiovascular system.10
blood cells do not have a nucleus, so they cannot produce new proteins in
response to oxidative damage. One way to support red blood cell health
Not only do antioxidants prevent damage to individual cells, they can
is to prevent oxidation through strong antioxidant supplementation.
also prevent the breakdown of nitric oxide (NO). NO is a gas naturally
produced in the cardiovascular system, which helps promote relaxation
Antioxidant supplementation is especially important for people whose
and expansion of the blood vessels. By supporting NO, antioxidant
red blood cell health is compromised due to anemia, including Sickle
supplementation can enhance blood flow. This explains why Jobelyn has
Cell Disease. Recent scientific studies have looked specifically at the
been found to enhance circulation.11
effects of Jobelyn on anemia and found that it effectively increases packed
cell volume (PCV – the sheer number of blood cells) and hemoglobin
The cardiovascular system also benefits from Jobelyn’s anti-inflammatory
concentration (Hb – an indicator of red blood cell health).3-7 Preliminary
effects. Fatty plaque build-up in blood vessels often occurs due to low-
human clinical research in Nigeria has confirmed these results, showing
grade inflammation and irritation throughout the vessel walls. This
some beneficial effects after just a week of supplementation and significant
inflammation makes it easier for cholesterol particles to stick to the
improvements for 102 of 113 patients after 6 weeks.8
lining of the blood vessels. Reducing inflammation can actually lower
the incidence of atherosclerosis (fatty plaque deposits) and coronary
In the case of Sickle Cell Disease, not only does Jobelyn help in its
events.1, 2, 10
antioxidant activity, but its anti-inflammatory properties may be of
. 4
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Joint Health – Just as oxidation and inflammation
Immune System Response – It takes a little
are at the core of blood cell and cardiovascular
more explanation to understand how Jobelyn
health threats, this troublesome duo is also
supports the immune system. As with the case
involved in causing joint degeneration and pain.
of red blood cell health, we need to drop down
The intricate connective tissue and surfaces
to a cellular and molecular level and think very
of our joints are under constant challenge
small. It’s the antioxidant activity that is most
from daily use. Ongoing wear and tear, along
vital for immune system support. Specifically,
with occasional injury, result in plenty of free radical production and
the extract provides components for the body to build its own super
inflammation. Without antioxidant support and balancing of the
antioxidant: glutathione peroxidase.
inflammation process, the result can be achy joints and limited range of
The body creates glutathione and uses it for several protective
motion.
tasks including protecting certain immune system cells called CD4
We’ve touched on the role of Jobelyn as a powerful antioxidant and a
T-lymphocytes. Glutathione contains selenium and three amino acids
very selective COX-2 inhibitor. Jobelyn has also demonstrated an ability
(cystein, glutamine, and tryptophan). Jobelyn contains all three of these
to inhibit the release of pro-inflammatory proteins called cytokines. We
amino acids, providing the body with some major building blocks of
learned how the combination of anti-inflammatory and antioxidant
glutathione.
support results in dramatic improvements for the cardiovascular system.
Scientists believe this explains some astounding research coming out of
The same benefits can improve joint health too.
Africa right now. In a preliminary human clinical study involving HIV-
In the joints, inflammation and oxidation create a self-reinforcing cycle.
positive patients, Jobelyn supplementation improved compromised CD4
Inflammation creates oxygen free radicals as a byproduct, which can in
cell counts (30-300/1) by 200-300%. Those with initial CD4 counts
turn cause more damage, which creates more inflammation, and so the
greater than 300 also saw an increase of 20-30%. The increase in cellular
cycle goes. Sorghum leaf sheath extract, which provides both antioxidant
immunity occurred regardless of whether the patient was taking other
and anti-inflammatory effects, has been found to bring a dynamic end
antiretroviral drugs.12
to this cycle.1, 2
Jobelyn is incredibly beneficial for the immune system when the body
A reduction in inflammation and pain means more range of motion and
is under one of the heaviest attacks imaginable. It makes sense that the
the freedom to work the joint and build strength. Strength-building
herbal would be helpful as a general immune system boost for anyone
through physical therapy helps prevent future injury. By ending a
in fine health. Its effects appear to be moderated too; meaning it won’t
damaging pain cycle, Jobelyn has been found to begin a positive cycle of
make the immune system become overactive. That’s why we see such a
improving joint health especially when combined with an appropriate
dramatic increase for those with very compromised CD4 counts and a
exercise program.
moderated increase for those who had higher initial counts. So, Jobelyn
is a safe immune support supplement whether you’re looking for a little
extra help during cold and flu season, or if you’re facing a much more
daunting immune system challenge.
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Taking Action:
Jobelyn – Heart Health Formula
Which Sorghum bicolor product is right for you?
Worldwide, there are remarkably few manufacturers producing antioxidant
A blend of Sorghum bicolor leaf extract with hawthorn
sorghum leaf extract. But, in the United States, there is one reputable
berry extract and alpha lipoic acid. The combination
company that makes the extract available under the brand name Jobelyn.
supports healthy heart rhythm and function along with
Named after the River Jubi region where the sorghum plant once grew
providing overall antioxidant protection for the heart,
wild, Jobelyn is produced under strict GMP standards and batch-tested
blood cells, and circulatory vessels.
for purity and efficacy.
Directions for Use:
Supplement Facts
Health Forever, the manufacturer who produces Jobelyn, offers the
Take one capsule, two or three
Serving Size: One (1) Capsule
Servings Per Container: 60
Sorghum bicolor leaf extract as a primary ingredient in four condition-
times daily with a 12 ounce
Amount
% Daily
glass of water. May be taken
specific products:
Per Serving
Value
regularly for ongoing support
Sorghum bicolor Leaf Powder .............250 mg
**
of cardiovascular health. In-
Hawthorn Berry Extract ..................... 80 mg
**
crease daily water intake when
Jobelyn – Blood Builder Formula
Alpha Lipoic Acid................................ 300 mg
**
taking Jobelyn products.
A blend of Sorghum bicolor leaf extract with additional
**Daily Value not established
antioxidant alpha lipoic acid and herbal Eleutherococcus
senticosus. Together, these components support blood
cell production, promote blood cell and vessel integrity,
Jobelyn – Joint Health Formula
and promote healthy cholesterol levels already within
the normal range.
A blend of Sorghum bicolor leaf extract along with the
Directions for Use:
Supplement Facts
well-known joint health supplement glucosamine.
Take one capsule, two or
These two ingredients provide synergistic joint and
Serving Size: One (1) Capsule
Servings Per Container: 60
three times daily with a 12
ounce glass of water, for
cartilage protection and support comfortable range of
Amount
% Daily
Per Serving
Value
as long as immune system
motion.
Sorghum bicolor Leaf Powder .............250 mg
**
support is desired. May be
taken regularly for ongoing
Alpha Lipoic Acid ............................. 300 mg
**
support of blood building
Directions for Use:
Eleuthero Root Extract ...................... 500 mg
**
Supplement Facts
activity. Increase daily water
Take one capsule, two or three
Serving Size: One (1) Capsule
Servings Per Container: 60
**Daily Value not established
intake when taking Jobelyn
times daily with a 12 ounce
products.
Amount
% Daily
glass of water. May be taken
Per Serving
Value
regularly for ongoing support
Sorghum bicolor Leaf Powder ............... 250 mg
**
of joint health. Increase daily
Glucosamine Sulfate................................ 80 mg
**
water intake when taking
(from Glucosamine Sulfate Potassium)
Jobelyn products.
**Daily Value not established
. 8
9 ,
Jobelyn – Immune Support Formula
Endnotes
1–Vivacell Biotechnology GMBH (2005) “Anti-Inflammatory effects of
A blend of Sorghum bicolor leaf extract with additional
Jobelyn” (Report: Phase I Results).
immune system supporting herbals Echinacea and
astragalus. May be taken regularly to keep the immune
2–Bensen E, MD-3-3-096-1083. MD Biosciences, Inc., USA, (2008).
system working at an optimum level or at the onset
“1-16 Evaluation of Four Compounds in an In vitro LPS-Stimulated
of symptoms to help the body get over an infection
Human PBMC Model”
faster.
(Report: Indirect Cox Activity Assay).
Supplement Facts
Directions for Use:
Take one capsule, two or
3–Okochi VI, Okpuzor J, Okubena MO, Awoyemi AK (2003). “The
Serving Size: One (1) Capsule
Servings Per Container: 60
three times daily with a 12
influence of African Herbal Formula on the haematological parameters
Amount
% Daily
ounce glass of water for
of trypanosome infected rats.” African Journal of Biotechnology 2(9): 312-316.
Per Serving
Value*
as long as immune system
Sorghum bicolor Leaf Powder ............... 250 mg
**
support is desired. May be
4–Obinwano C., M.D. (1998). Independent preliminary clinical research.
Echinacea purpurea Root Extract 4% . 113 mg
**
taken regularly for long-
term support of immune
Golden Heart Medical Centre; Lagos, Nigeria. Supplementation with
Astragalus Root Extract 10:1 ............... 150 mg
**
system. Increase daily water
Sorghum bicolor leaf sheath extract connected to significant improvements
**Daily Value not established
intake when taking Jobelyn
in cases of anemia resulting from severe malaria, sickle cell anemia, enteric
products.
fever, helminthiasis, and acute lymphoblastic leukemia, and one case of
E
severe arthritis.
ven if these particular condition-specific formulas are not of interest,
two of them are perfect for general health and wellness. The Heart
5–Erah PO, Asonye CC, Okhamafe AO (2003). “Response of
Health and Joint Health Formulas contain the most versatile herbal
Trypanosoma brucei brucei-induced anaemia to a commercial herbal
blends that are beneficial to anyone, no matter what their health goals are.
preparation.” African Journal of Biotechnology. 2(9): 307-311.
If you’re interested in simply experiencing the effects of Sorghum bicolor
leaf extract, these two products are a great place to start.
6–Ogwumike OO (2002). “Hemopoietic effect of aqueous extract of the
Jobelyn products are the most trusted source of traditional Sorghum bicolor
leaf sheath of Sorghum bicolor in albino rats.” African Journal of Biomedical
leaf extract worldwide. In fact, it was specifically the Jobelyn sorghum
Research. 5(1-2): 69-71.
leaf extract that was used as the ingredient source for most of the studies
7–Okochi V, Okpuzor J, Alli LA (2003). “Comparison of an African
cited in this booklet. Whenever you’re shopping for an herbal product,
herbal formula with commercially available haematinics.” African Journal
that’s one of the most important qualities to look for—a company that
of Biotechnology. 2(8): 237-240.
has had its own ingredient subjected to scientific studies.
Regardless of the specific Jobelyn product you choose, you can rest assured
8–Abia-Okon, DA, M.D. (2008). Independent preliminary clinical
that it will be safe13 and effective. Within three to four weeks, you’ll be
research. Lindabel Medical Centre; Lagos, Nigeria. Significant
surprised at the health-changing results. Sorghum bicolor leaf extract has
improvements in Hb and PCV values in 90% of 113 anemic subjects
been a trusted remedy for centuries in traditional African medicine, and
supplemented with 250 mg of Sorghum bicolor leaf sheath extract two
now it’s finally available to the rest of the world. May you discover
times daily for 7 days.
increased wellness and renewed energy as you provide your body with
9–Platt, OS (2000). “Sickle cell anemia as an inflammatory disease.” The
the antioxidant and natural anti-inflammatory support it needs!
Journal of Clinical Investigation. 106(8): 337–338.
.10
11 ,
10–Singh RB, Niaz MA, Agarwal P, Begom R, Rastogi SS (1995).
“Effect of antioxidant-rich foods on plasma ascorbic acid, cardiac enzyme,
and lipid peroxide levels in patients hospitalized with acute myocardial
Where to get Jobelyn
infarction.” Journal of the American Dietetic Association. 95(7): 775-780.
11–Kumar CA, Das UN (2000). “Lipid peroxide, antioxidants and nitric
oxide in patients with preeclampsia and essential hypertension.” Medical
Science Monitor. 6(5): 901-907.
12–Ayuba G, Col. (2003). Independent preliminary clinical research.
Military Hospital, Lagos, Nigeria. Findings: Supplementation with extract
of Sorghum bicolor leaf sheath found to increase CD4 cell counts in HIV
positive subjects when used alone or in combination with ARDs.
13–Eniojukan JF, Aina BA (2009). “Toxicological Profiles of Commercial
Herbal Preparation, Jobelyn®.” International Journal of Health Research.
2(4): 369-374.
Health Forever – Jobelyn Products
Manufactured for distribution in USA by:
Hains Herbal Product, LLC
1.888.328.5279
www.health-forever.com
info@ health-forever.com
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About the Author
With a medical career that has
spanned Europe and Africa,
David Abia-Okon, MD is now
the Medical Director at Lindabel
Medical Centre in Lagos, Nigeria.
In his own practice, he specializes
in general and vascular surgery. He
is also intrigued by natural products
and enjoys developing treatment programs that utilize the
best of both mainstream medicine and alternative health.
Dr. Abia-Okon had heard of Sorghum bicolor folk remedies,
but it wasn’t until he had some professional experience
with the extract that he became convinced of its incredible
antioxidant power and protective effects. Colleagues in
Nigeria had conducted studies on a standardized extract
based on the folk remedy and found it helpful for sickle cell
anemia and immune system compromised patients. This
caught Dr. Abia-Okon’s attention, and he began studying
the extract in his own practice. Conducting preliminary
clinical research and reviewing other published studies, he
became convinced of the extract’s power to spark incredible
improvement in a wide variety of health conditions where
inflammation and oxidation are chief aggravating factors.
Dr. Abia-Okon continues to practice in Nigeria, dedicated
to discovering and implementing the best health care
approaches for each individual patient. He is a member of
the Nigerian Medical Association and the Association of
General and Private Medical Practitioners of Nigeria.
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