This is not the document you are looking for? Use the search form below to find more!

0.00 (0 votes)

volume of distribution

- Added:
**June, 03rd 2012** - Reads:
**956** - Downloads:
**8** - File size:
**569.64kb** - Pages:
**11** - content preview

- Username: hma.pharma
- Name:
**hma.pharma** - Homepage: https://www.facebook.com/hamza.ashur
- Documents:
**12**

Related Documents

A sphere is a rounded geometrical object in 3 – D like the shape of a round ball. A circle is a two dimensional object while a sphere is completely symmetrical around its center having all ...

Volume of a Sphere is a measurement of the occupied units of a Sphere. The volume of a Sphere is represented by cubic units like cubic centimeter, cubic millimeter and so on. Volume of a Sphere is ...

olume of a Sphere is a measurement of the occupied units of a Sphere. The volume of a Sphere is represented by cubic units like cubic centimeter, cubic millimeter and so on. Volume of a Sphere is the ...

A sphere is a rounded geometrical object in 3 – D like the shape of a round ball. A circle is a two dimensional object while a sphere is completely symmetrical around its center having all ...

Mathematics is a very wide area in which we calculate volumes for various geometries shapes, these shapes have definite shape and size the shapes are cube, cone, sphere, cylinder. But here we have to ...

We can find volume of sphere by a simple formula, but first of all we need to learn about the sphere. Sphere is comparable to a circle. As we know that circle can be represented in two dimensions we ...

We can find volume of sphere by a simple formula, but first of all we need to learn about the sphere. Sphere is comparable to a circle. As we know that circle can be represented in two dimensions we ...

In mathematics, there are different types of prism such as triangular prism, rectangular prism and so on. Here we will proceed to Volume of a Prism. Before learning about Volume of a Prism first it ...

In mathematics, there are different types of prism such as triangular prism, rectangular prism and so on. Here we will proceed to Volume of a Prism. Before learning about Volume of a Prism first it ...

Boolean Algebra is logical calculation of the truth values. It was developed by George Boole in the year 1840. It is similar to the algebra of the real numbers. But the binary operations like ...

Content Preview

intracellular fluid.

body water and can never exceed body water.

Plasma

3 - 4

Interstitial

10 - 13

Intracellular

25 - 28

Total body water

40 - 46

volume. This would happen only if the drug is

uniformly

same and the Volume is the

same as the size of the

beaker.

equilibrium, distribution b/n

the solution and the charcoal

may be complete. However,

drug conc. within the beaker

is not uniform. Much of the

drug

theoretical volume of fluid (not only plasma) into

which the total drug administered would have to

be diluted to produce the concentration in

plasma.

the actual volume of the body or its fluid

compartments

comparatively little of a dose remains in the

circulation to be measured; thus, plasma

concentration is low and volume of distribution

is high. Drugs that remain in the circulation tend

to have a low volume of distribution.

the plasma concentration expected for a given

dose. Each drug is uniquely distributed in the

body. Some drugs distribute mostly into fat,

others remain in ECF, and others are bound

extensively to specific tissues.

protein-bound and thus have a small volume of

distribution.

extensively taken up by tissues and thus have a

volume of distribution larger than the volume of

the entire body.

plasma concentration. A parameter used to define the

process of distribution and called "the apparent volume

of distribution (V )".

## Add New Comment