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ISOLATING BEHAVIORAL MECHANISMS OF INTERTEMPORAL CHOICE: NICOTINE EFFECTS ON DELAY DISCOUNTING AND AMOUNT SENSITIVITY

by: shinta, 11 pages

Many drugs of abuse produce changes in impulsive choice, that is, choice for a smaller–sooner reinforcer over a larger–later reinforcer. Because the alternatives differ in both ...

QUANTIFICATION OF DRUG CHOICE WITH THE GENERALIZED MATCHING LAW IN RHESUS MONKEYS

by: shinta, 16 pages

The generalized matching law provides precise descriptions of choice, but has not been used to characterize choice between different doses of drugs or different classes of drugs. The current ...

ACQUISITION OF COCAINE SELF-ADMINISTRATION WITH UNSIGNALED DELAYED REINFORCEMENT IN RHESUS MONKEYS

by: shinta, 12 pages

Six experimentally naive rhesus monkeys produced 0.01 mg/kg/infusion cocaine by lever pressing under a tandem fixed-ratio 1 differential-reinforcement-of-other-behavior schedule. One lever ...

EFFECTS OF REINFORCEMENT SCHEDULE ON FACILITATION OF OPERANT EXTINCTION BY CHLORDIAZEPOXIDE

by: shinta, 12 pages

Learning and memory are central topics in behavioral neuroscience, and inbred mice strains are widely investigated. However, operant conditioning techniques are not as extensively used in this ...

PILOCARPINE SEIZURES CAUSE AGE-DEPENDENT IMPAIRMENT IN AUDITORY LOCATION DISCRIMINATION

by: shinta, 14 pages

Children who have status epilepticus have continuous or rapidly repeating seizures that may be life- threatening and may cause life-long changes in brain and behavior. The extent to which ...

THE ROLE OF DOPAMINE IN REINFORCEMENT: CHANGES IN REINFORCEMENT SENSITIVITY INDUCED BY D1-TYPE, D2-TYPE, AND NONSELECTIVE DOPAMINE RECEPTOR AGONISTS

by: shinta, 29 pages

Dose-dependent changes in sensitivity to reinforcement were found when rats were treated with low, moderate, and high doses of the partial dopamine D1-type receptor agonist SKF38393 and with ...

EFFECTS OF COCAINE ON FIXED-INTERVAL RESPONDING REINFORCED BY THE OPPORTUNITY TO RUN

by: shinta, 15 pages

Rate-dependent drug effects have been observed for operant responding maintained by food, water, heat, light onset, electrical brain stimulation, shock-stimulus termination, and shock ...

BEHAVIORAL AND PHARMACOLOGICAL VARIABLES AFFECTING RISKY CHOICE IN RATS

by: shinta, 23 pages

The effects of manipulations of response requirement, intertrial interval (ITI), and psychoactive drugs (ethanol, phencyclidine, and d-amphetamine) on lever choice under concurrent ...

DRUG DISCRIMINATION: STIMULUS CONTROL DURING REPEATED TESTING IN EXTINCTION

by: shinta, 12 pages

Rats were trained, under a two-lever drug-discrimination procedure, to respond differentially de- pending upon whether lorazepam (1.0 mg/kg) or no injection had been administered before the

BEHAVIOR OF RATS UNDER FIXED CONSECUTIVE NUMBER SCHEDULES: EFFECTS OF DRUGS OF ABUSE

by: shinta, 16 pages

Four rats responded under a simple fixed consecutive number schedule in which eight or more consecutive responses on the run lever, followed by a single response on the reinforcement lever,

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